[water_into_wine]

Not necessary to start from the beginning, especially because there are so many. I'd do what I'm doing know, which is subscribing (and thus getting them bi-weekly at the moment) and seeing if you like the show and getting used to the format. Then when you have time go back to the beginning. You'll never be completely lost in any given episode, but you will miss some inside jokes. Aukerman is one of the best hosts and almost directs the chaos, so whenever there is a major callback he'll suually give a quick aside to explain that it happened previously.

Also the show kinda blew for the first few episodes as it didn't really know what it was at the time.